Bovine Factor V/Va Purified from Innovative Research has been purified from bovine plasma using salt precipitations and column chromatography. This is a frozen liquid buffered in 20 mM HEPES-HCl/0.15 M NaCl/pH 7.4/50% glycerol and is a mixture of Factor V/Va as well as intermediate activation products, as determined by 4-20% gradient gels. This product functions as a source of Factor V/Va in the prothrominase complex. Factor V is a cofactor (and not enzymatically active). Factor V binds to activated platelets and is activated by thrombin. When activated, Factor Va contains two chains (heavy and light) and is a cofactor of prothrombinase complex. Factor Va is degraded by Activated Protein C. More Details: Source: Bovine Plasma freshly collected from US Origin animals less than or equal to 3 years of age. Purification: Salt Precipitations and Column Chromatography Purity: Mixture of Factor V/Va and intermediate activation products as determined by 4-20% gradient gels. Storage Conditions: -20░C At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results. Please note ¢ this product replaces our old product number IBFV/Va (same product, new number).